Photobacterium damselae - Pasteurellosis

Introduction

Pasteurellosis is caused by the gram-negative and halophilic bacterium Photobacterium damselae. The disease affects a wide range of marine species, and fish can harbor the bacterium as subclinical infection for long periods of time. VESO Aqualab offers challenge models with Photobacterium damselae.

Challenge model to evaluate the efficacy of vaccination

Seabass (average weight 4-10 grams) are acclimatized to 20°C for a minimum of two weeks before vaccination. After a four-week immunization period, fish are challenged by i.p. injection. After challenge, mortality is recorded during an observation period of 21 days. Evaluation of the potency of the vaccine is based on differences in mortality in vaccinated and unvaccinated groups.

Mortality in groups of vaccinated and unvaccinated seabass i.p. injected with Photobacterium damselae.